| REVIEW ARTICLE |
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| Year : 2020 | Volume
: 8
| Issue : 2 | Page : 61-66 |
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De-escalation Strategies in Human Papilloma Virus-Positive Oropharyngeal Cancer
Vishal Gupta
Department of Head and Neck/Plastic Reconstructive Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA
Correspondence Address:
Vishal Gupta
Department of Head and Neck/Plastic Reconstructive Surgery, Roswell Park Comprehensive Cancer Center, Elm and Cartlon Streets, Buffalo, NY 14263
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jhnps.jhnps_29_20
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Human papilloma virus (HPV) is now attributable to most of the oropharyngeal squamous cell cancers (OPSCCs) occurring in western world. The HPV-associated OPSCC effect younger, otherwise healthy population and is typically associated with better outcome. Traditional treatment strategies, while successful, are associated with significant long-term morbidity and poorer quality of life. This has led to various trials and investigations to de-escalate the treatment in this patient population while maintaining excellent outcome. The objective of this review is to discuss various de-escalation strategies and trials.
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